Mutational spectrum of the mitochondrial genome

Birds are a vertebrate class with one of the highest basal metabolic rates across all animals. So the question arises: does their mtDNA have nucleotide content and mutational bias shift due to Ah->Gh and Ch -> Th (h – heavy chain) mutations? 

Our hypotheses:

  1. Birds should have more G and T on the mtDNA in four-fold positions
  2. Amount of G and T should grow with increase with each gene specific time being single stranded
  3. Birds with high basal metabolism rate – antarctic ecozone and herbivore aquatic trophic niche should have higher amount of G and T due to Ah->Gh and Ch->Th
  4. Mutagenesis is the main reason for birds mtDNA nucleotide content shift
0

Автор публикации

не в сети 3 месяца

MitoFunGen

0
Комментарии: 0Публикации: 12Регистрация: 31-01-2023
Авторизация
*
*
Генерация пароля